Applies to didanosine chewable tablets and powder for oral solution; administer 2 hr before or several hours after didanosine oral solution or chewable tablet administration. Applies only to oral form of both agents. Applies only to oral form of both agents. The dosage of Venofer is expressed in mg of elemental iron. Nutrition. To view formulary information first create a list of plans. May increase risk of hypotension. Coadministration of ciprofloxacin with multivalent cation-containing products may reduce the bioavailability of ciprofloxacin by 90%. Avoid or Use Alternate Drug. Most J Lab Clin Med. HOW TO USE: This medication is given by injection into a vein as directed by your doctor. For iron maintenance treatment: Administer Venofer at a dose of 0.5 mg/kg, not to exceed 100 mg per dose, every four weeks for 12 weeks given undiluted by slow intravenous injection over 5 minutes or diluted in 0.9% NaCl at a concentration of 1 to 2 mg/mL and administered over 5 to 60 minutes. All Rights Reserved. We comply with the HONcode standard for trustworthy health information. Total cumulative Venofer dose = number of 100mg ampoules for Hb increase. Use Caution/Monitor. If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. famotidine will decrease the level or effect of iron sucrose by increasing gastric pH. Applies only to oral form of both agents. Iron Sucrose Dosage Guide + Max Dose, Adjustments - Drugs.com Iron sucrose can also be mixed in a saline solution and given through an IV over a longer time. Your doctor will do laboratory tests to monitor your response. Med J Aust; 193(9):525-32. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.In Canada - Call your doctor for medical advice about side effects. Interaction only with oral iron administration. Perinatology and Obstetrical Calculators The prevention and treatment of iron deficiency is a major public health goal, especially in women, children, and individuals in low-income countries. 0.5 mg/kg (not to exceed 100 mg/dose) diluted to a concentration of 1 to 2 mg/mL in 0.9% sodium chloride IV over 5 to 60 minutes Administer every 4 weeks for 12 weeks Do not dilute to concentrations below 1 mg/mL Comments: Treatment may be repeated if necessary. FERAHEME vs Venofer (iron sucrose) - Feraheme Monitor Closely (1)sodium bicarbonate will decrease the level or effect of iron sucrose by increasing gastric pH. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Give each dose as 750mg for a total cumulative dose not to exceed1500mg of ironper course. It is important to note that the above calculations merely provide estimates and that individual dosage should be established by a medical professional based on the current package insert for the elemental iron product used. 1 ,*. Do not dilute to concentrations below 1 mg/mL [see How Supplied/Storage and Handling (16.2).] Minor/Significance Unknown. Applies only to oral form of both agents. Venofer treatment may be repeated if necessary. Venofer must only be administered intravenously either by slow injection or by infusion. Applies only to oral form of both agents. Use Caution/Monitor. Applies only to oral form of both agents. The dosage of Venofer is expressed in mg of elemental iron. Monitor Closely (1)iron sucrose decreases levels of ibandronate by inhibition of GI absorption. Each mL contains 20 mg of elemental iron. Mean Corpuscular Hemoglobin Concentration (MCHC) Calculator, Red Blood Cell (RBC) Indices Calculator, Iron Deficiency In Pregnancy Calculator. Individual doses of 2 mL or less may be given on a daily basis until the calculated total amount required has been reached. DOSAGE AND ADMINISTRATION: Oral iron should be discontinued prior to administration of INFeD. The Ganzoni equation used by the iron deficiency calculator is the following: Total iron deficit (mg) = Weight in kg x (Target Hb - Actual Hb in g/dL) x 2.4 + Iron stores. This health tool computes the iron deficit based on patient parameters and the Ganzoni formula. Applies only to oral form of both agents. Serious - Use Alternative (1)iron sucrose decreases levels of oxytetracycline by inhibition of GI absorption. Venofer may cause clinically significant hypotension. Where C is the concentration of the iron product: Please note that the calculations above are for information purposes only and the individual dose needs to be established by taking into account the current package insert for the elemental iron product used. Pasricha SR, Flecknoe-Brown SC, Allen KJ, Gibson PR, McMahon LP, Olynyk JK, Roger SD, Savoia HF, Tampi R, Thomson AR, Wood EM, Robinson KL. Can't find what you need? Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. Applies only to oral form of both agents. Equations : Total body iron deficit (mg) = body weight (kg) x (target Hb - actual Hb in g/dL) x 2.4 + iron depot (mg)** [1, 2] Iron depot: 15 mg/kg for body weight less than 35 kg 500 mg for those with a body weight greater than or equal to 35 kg Ideal Body Weight (kg) =45.5 +2.3 * (height inches - 60 inches) [3] After total replacement dose completed, need for ongoing IV doses should be re-assessed monthly. Studies in monkeys showed concurrent use with calcium, aluminum, or iron caused significantly decreased plasma levels. Iron Deficit - Multi-Calc - GlobalRPH - Medical Calculators, Clinicians IDA symptoms vary, may not be specific and include tiredness, weakness, shortness of breath. Copyright 1993-2021 Monitor Closely (1)iron sucrose decreases levels of liothyronine by inhibition of GI absorption. One dose IV Iron replacement | Monoferric Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. PDF Injectafer (ferric carboxymaltose injection) - Food and Drug Administration Parenteral iron dose - UpToDate Dilute Venofer in a maximum of 250 mL of 0.9% NaCl [see How Supplied/Storage and Handling (16.2).] LBW = Lean body weight in kg. Serum iron, total iron binding capacity (TIBC) and percent saturation of transferrin are other important tests for detecting and monitoring the iron deficient state. Iron deficiency anemia is the type of anemia caused by iron depletion. Applies only to oral form of both agents. 2.1 Dosage - Total dose infusion The dose calculation for CosmoFer is based on patients body weight according to the table below and is diluted in 500mLs of normal saline. We have found the lower dose to be better tolerated in the second half of gestation. Monofer 100mg/ml solution for injection/infusion - Summary of Product Venofer Injection Dosage Guide - Drugs.com This drug is available at a higher level co-pay. DOSAGE AND ADMINISTRATION: The recommended dose of Feraheme is an initial 510 mg dose followed by a second 510 mg dose 3 to 8 days later. For iron maintenance treatment: Administer Venofer at a dose of 0.5 mg/kg, not to exceed 100 mg per dose, every four weeks for 12 weeks given undiluted by slow intravenous injection over 5 minutes or diluted in 0.9% NaCl at a concentration of 1 to 2 mg/mL and administered over 5 to 60 minutes. Diagnosis and management of iron deficiency anaemia: a clinical update. Multivalent cation-containing products may impair absorption of tetracyclines, which may decrease its efficacy. Intravenous Injection - PRIOR TO THE FIRST INTRAVENOUS INFeD THERAPEUTIC DOSE, ADMINISTER AN INTRAVENOUS TEST DOSE OF 0.5 ML. 2010; 193(9):525-32. Use Caution/Monitor. Monitor Closely (1)sodium citrate/citric acid will decrease the level or effect of iron sucrose by increasing gastric pH. ibuprofen/famotidine will decrease the level or effect of iron sucrose by increasing gastric pH. 2012;2(4):288-335. Option 2: 200 mg in NS 100 mL administered over 20-30 minutes; may repeat every other day to Canada residents can call a provincial poison control center. Applies only to oral form of both agents. This parenteral iron replacement for iron deficiency anemia calculator determines the parenteral dose of iron supplement needed to replenish iron stores and hemoglobin levels. Avoid or Use Alternate Drug. Applies only to oral form of both agents. The dosage of Venofer is expressed in mg of elemental iron. FERAHEME met the predefined criteria for non-inferiority to Venofer . calcium carbonate decreases levels of iron sucrose by inhibition of GI absorption. FOR PATIENTS WEIGHING LESS THAN 50 kg: Administer Monoferric as 20 mg/kg actual body weight by intravenous infusion 20 minutes . If hypersensitivity reactions or signs of intolerance occur during administration, stop Venofer immediately. Serious - Use Alternative (1)iron sucrose decreases levels of levofloxacin by inhibition of GI absorption. Adult Patients with Non-Dialysis Dependent-Chronic Kidney Disease (NDD-CKD): Administer Venofer 200 mg undiluted as a slow intravenous injection over 2 to 5 minutes or as an infusion of 200 mg in a maximum of 100 mL of 0.9% NaCl x 15 minutes. iron sucrose decreases levels of manganese by inhibition of GI absorption. Applies only to oral form of both agents. Intravenous therapy is usually recommended in case of contraindications to oral iron, comorbidities that prevent absorption, chronic renal impairment or iron replacement needs to be rapid. Venofer [package insert]. informational and educational purposes only. Applies only to oral form of both agents. Use Caution/Monitor. Use Caution/Monitor. Applies only to oral form of both agents. Multivalent cation-containing products may impair absorption of tetracyclines, which may decrease its efficacy. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Calculation of the Total Iron Deficit - Alternative equation Consult your pharmacist or local waste disposal company. Applies only to oral form of both agents. Avoid or Use Alternate Drug. The weight of the patient is taken into account in order to estimate iron stores, while haemoglobin is required as both current measured and target. Minor/Significance Unknown. iron sucrose increases levels of calcium acetate by enhancing GI absorption. iron sucrose decreases levels of levofloxacin by inhibition of GI absorption. pantoprazole will decrease the level or effect of iron sucrose by increasing gastric pH. Last updated on Jun 1, 2022. Use Caution/Monitor. Applies only to oral form of both agents. This website is intended for use by US healthcare professionals only. Separate dosing of tetracyclines from these products. May increase risk of hypotension. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.This is not a complete list of possible side effects.
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